中国食品药品检定研究院安全评价研究所根据世界卫生组织国际癌症研究机构2017年10月27日公布的致癌物清单初步整理,仅供参考。
世界卫生组织国际癌症研究机构致癌物清单
1类致癌物清单(116种)
1类致癌物:对人类为确定致癌物。
序号 英文名称 中文名称 确定时间(年)
1 Acetaldehyde associated with consumption of alcoholic beverages 随酒精饮料摄入的乙醛 2012
2 Acheson process, occupational exposure associated with 艾其逊法(用焦炭和粘土混合加热制造石墨的工业方法),职业暴露相关 2017
3 Acid mists, strong inorganic 强无机酸雾 2012
4 Aflatoxins 黄曲霉毒素 2012
5 Alcoholic beverages 酒精饮料 2012
6 Aluminium production 铝产品 2012
7 4-Aminobiphenyl 4-氨基联苯 2012
8 Areca nut 槟榔果 2012
9 Aristolochic acid 马兜铃酸 2012
10 Aristolochic acid, plants containing 包含马兜铃酸的植物 2012
11 Arsenic and inorganic arsenic compounds 砷和无机砷化合物 2012
12 Asbestos (all forms, including actinolite, amosite, anthophyllite, chrysotile, crocidolite, tremolite) 铁石棉,石棉(各种形式,包括阳起石直闪石,温石棉,青石棉、透闪石) 2012
13 Auramine production 金胺制造 2012
14 Azathioprine 硫唑嘌呤 2012
15 Benzene 苯 2012
16 Benzidine 对二氨基联苯 2012
17 Benzidine, dyes metabolized to 联苯胺、染料代谢 2012
18 Benzo[ a ]pyrene 苯并芘 2012
19 Beryllium and beryllium compounds 铍和铍化合物 2012
20 Betel quid with tobacco 含烟草的槟榔嚼块 2012
21 Betel quid without tobacco 不含烟草的槟榔嚼块 2012
22 Bis(chloromethyl)ether; chloromethyl methyl ether (technical-grade) 二氯甲基醚;一氯甲基醚(技术等级) 2012
23 Busulfan 白消安 2012
24 1,3-Butadiene 1,3-丁二烯 2012
25 Cadmium and cadmium compounds 镉及镉化合物 2012
26 Chlorambucil 苯丁酸氮芥 2012
27 Chlornaphazine 萘氮芥 2012
28 Chromium (VI) compounds 铬(VI)化合物 2012
29 Ciclosporin 环孢素 2012
30 Clonorchis sinensis (infection with) 华支睾吸虫(感染) 2012
31 Coal gasification 煤的气化 2012
32 Coal, indoor emissions from household combustion of 家庭燃烧的煤,室内排放 2012
33 Coal-tar distillation 煤焦油蒸馏 2012
34 Coal-tar pitch 煤焦油沥青 2012
35 Coke production 焦炭制造 2012
36 Cyclophosphamide 环磷酰胺 2012
37 Cyclosporine 环孢霉素 2012
38 1,2-Dichloropropane 1,2-二氯丙烷 2016
39 Diethylstilbestrol 己烯雌酚 2012
40 Engine exhaust, diesel 发动机排放、柴油 2013
41 Epstein-Barr virus 巴尔病毒 2012
42 Erionite 毛沸石 2012
43 Estrogen therapy, postmenopausal 雌激素治疗绝经后 2012
44 Estrogen-progestogen menopausal therapy (combined) 雌激素-孕激素更年期治疗(联合) 2012
45 Estrogen-progestogen oral contraceptives (combined) 雌激素-孕激素口服避孕药(组合) 2012
46 Ethanol in alcoholic beverages 酒精饮料中的乙醇 2012
47 Ethylene oxide 环氧乙烷 2012
48 Etoposide 依托泊苷 2012
49 Etoposide in combination with cisplatin and bleomycin 依托泊苷结合顺铂和博来霉素 2012
50 Fission products, including strontium-90 裂变产物,包括锶- 90 2012
51 Fluoro-edenite fibrous amphibole 氟代-浅闪石纤维角闪石 2017
52 Formaldehyde 甲醛,福尔马林 2012
53 Haematite mining (underground) 赤铁矿矿业(地下) 2012
54 <i>Helicobacter pylori</i> (infection with) 幽门螺杆菌(感染) 2012
55 Hepatitis B virus (chronic infection with) 乙型肝炎病毒(慢性感染) 2012
56 Hepatitis C virus (chronic infection with) 丙型肝炎病毒(慢性感染) 2012
57 Human immunodeficiency virus type 1 (infection with) 人类免疫缺陷病毒I型(感染) 2012
58 Human papillomavirus types 16, 18, 31, 33, 35, 39, 45, 51, 52, 56, 58, 59 人类乳头瘤病毒类型16,18,31,33,35,39,45,51,52,56,58,59 2012
59 Human T-cell lymphotropic virus type I 人类T淋巴细胞病毒I型 2012
60 Ionizing radiation (all types) 电离辐射(所有类型) 2012
61 Iron and steel founding (occupational exposure during) 钢铁铸造(职业暴露) 2012
62 Isopropyl alcohol manufacture using strong acids 使用强酸生产异丙醇 2012
63 Kaposi sarcoma herpesvirus 卡波济肉瘤疱疹病毒 2012
64 Leather dust 皮革尘埃 2012
65 Magenta production 品红制造 2012
66 Melphalan 美法仑 2012
67 Methoxsalen (8-methoxypsoralen) plus ultraviolet A radiation "甲氧沙林
甲氧补骨脂素
花椒毒素
+紫外线辐射" 2012
68 Methyl-CCNU 甲基环已亚硝脲 2012
69 4,4'-Methylenebis(2-chloroaniline) (MOCA) 4,4'-亚甲基(2-氯苯胺) 2012
70 Mineral oils, untreated or mildly treated 矿物油,未经处理或温和治疗 2012
71 MOPP and other combined chemotherapy including alkylating agents MOPP(氮芥、长春新碱、甲基苄肼、强的松)和其他联合化疗包括烷化剂 2012
72 2-Naphthylamine 2-萘胺 2012
73 Neutron radiation 中子辐射 2012
74 Nickel compounds 镍化合物 2012
75 N'-Nitrosonornicotine (NNN) and 4-(N-Nitrosomethylamino)-1-(3-pyridyl)-1-butanone (NNK) 亚硝基降烟碱,亚硝胺 2012
76 Opisthorchis viverrini(infection with) 泰国肝吸虫(麝猫后睾吸虫、香猫肝吸虫)(感染) 2012
77 Outdoor air pollution 室外空气污染 2016
78 Outdoor air pollution, particulate matter in 室外空气污染,颗粒物 2016
79 Painter (occupational exposure as a) 画家(职业暴露) 2012
80 3,4,5,3’,4’-Pentachlorobiphenyl (PCB-126) 多氯联苯 2012
81 2,3,4,7,8-Pentachlorodibenzofuran 多氯二苯并呋喃 2012
82 Phenacetin 非那西汀 2012
83 Phenacetin, analgesic mixtures containing 非那西汀,包含止痛剂混合物 2012
84 Phosphorus-32, as phosphate 磷-32,磷酸 2012
85 Plutonium 钚 2012
86 Polychlorinated biphenyls 多氯联苯 2016
87 Polychlorinated biphenyls, dioxin-like, with a Toxicity Equivalency Factor (TEF) according to WHO (PCBs 77, 81, 105, 114, 118, 123, 126, 156, 157, 167, 169, 189) 类二恶英多氯联苯,毒性等价系数(TEF)取自WHO(多氯联苯77,77,81,77,81,123,126,156,157,167,169,189) 2016
88 Radioiodines, including iodine-131 放射性碘,包括碘- 131 2012
89 Radionuclides, alpha-particle-emitting, internally deposited 放射性核素,α粒子放射,内部沉积 2012
90 Radionuclides, beta-particle-emitting, internally deposited 放射性核素,β粒子放射,内部沉积 2012
91 Radium-224 and its decay products 镭- 224及其衰变产物 2012
92 Radium-226 and its decay products 镭- 226及其衰变产物 2012
93 Radium-228 and its decay products 镭- 228及其衰变产物 2012
94 Radon-222 and its decay products 氡- 222及其衰变产物 2012
95 Rubber manufacturing industry 橡胶制造业 2012
96 Salted fish, Chinese-style 中国式咸鱼 2012
97 Semustine [1-(2-Chloroethyl)-3-(4-methylcyclohexyl)-1-nitrosourea, Methyl-CCNU] 司莫司丁(甲基环己亚硝脲) 2012
98 Shale oils 页岩油 2012
99 Silica dust, crystalline, in the form of quartz or cristobalite 二氧化硅粉尘、水晶、石英、方石英的形式 2012
100 Solar radiation 太阳辐射 2012
101 Soot (as found in occupational exposure of chimney sweeps) 烟尘(发现于烟囱清洁工的职业暴露) 2012
102 Sulfur mustard 硫芥 2012
103 Tamoxifen 它莫西芬 2012
104 2,3,7,8-Tetrachlorodibenzo-para-dioxin 四氯双苯环二噁英(TCDD) 2012
105 Thiotepa 三胺硫磷 2012
106 Thorium-232 and its decay products 钍- 232及其衰变产物 2012
107 Tobacco smoke, second-hand 吸二手烟 2012
108 Tobacco smoking 吸烟 2012
109 Tobacco, smokeless 无烟烟草 2012
110 ortho-Toluidine 邻甲苯胺 2012
111 Treosulfan "苏消安
曲奥舒凡" 2012
112 Trichloroethylene 三氯乙烯 2014
113 Ultraviolet-emitting tanning devices 紫外线放射日光浴设备 2012
114 Vinyl chloride 氯乙烯 2012
115 Wood dust 木粉 2012
116 X- and Gamma-Radiation X、γ辐射 2012